Site Maastricht University
Type 2 diabetes is a severe chronic disease urgently needing new treatment options. We are looking for a highly self-motivated Msc student, preferably with a degree in (Technical) Medicine or Biomedical Sciences who is looking for an ambitious PhD project. The PhD student will be involved in small-scale human studies, in which she/he will perform drug and/or lifestyle interventions in type 2 diabetes patients or people at risk to develop type 2 diabetes. The effects of these interventions will be thoroughly investigated using high-end non-invasive imaging techniques (MRI/MRS, PET) combined with indirect calorimetry measurements and hyperinsulinemic-euglycemic clamps. In addition, muscle biopsies will provide more in-depth molecular information.
A strong (international) research group and -network is available to aid in the execution of the project and to receive additional training.
MSc in (Technical) Medicine, Biomedical Sciences or equivalent, with demonstrated affinity and/or experience with non-invasive imaging techniques, human intervention research and an interest in metabolic research. A degree as Medical Doctor/Technical Physician is a strong advantage. Good communication and organizational skills are required as well as qualifications to work in a team. Due to interaction with test subjects, mastering the Dutch language is a prerequisite (or needs to be acquired).
Within our translational research group (www.dmrg.nl), embedded in the department of Nutrition and Movement Sciences and within the Nutrim School of Nutrition and Translational Research in Metabolism at Maastricht University, we perform human clinical and experimental trials to unravel the aetiology of type 2 diabetes. We have special interest in human skeletal muscle and liver metabolism and we apply whole-body, tissue and cellular approaches to study mechanisms that lead to the development of insulin resistance and type 2 diabetes mellitus. To this end, Maastricht University has unique facilities to perform human translational studies (Metabolic Research Unit Maastricht, MRUM), which includes clamp facilities, whole body respiration chambers and access to magnetic resonance imaging and -spectroscopy (MRI/MRS) and positron emission tomography (PET) at the Maastricht University Medical Center.
Dr. J. Hoeks, Department of Nutrition and Movement Sciences, Maastricht University
Dr. V. Schrauwen, Department of Radiology and Nuclear Medicine, Maastricht University
Dr. M.Buitinga, Department of Radiology and Nuclear Medicine, Maastricht University. Email: M.Buitinga@maastrichtuniversity.nl